What is Stability and Why is it Important?

Stability is defined as a change (or lack of change) in accuracy over a period of time.

Drift is commonly used as a specification to illustrate the stability, or change in accuracy over a period of time, commonly shown as X%/year where X = a number; i.e. 0.25%/year. In this scenario, a device with a ±1% accuracy, would be expected to have an accuracy of ±1.25% (1%+0.25%) after a period of one year. Depending on the design, brand, and range of the sensing instrument, the stability can vary widely. Continue reading “What is Stability and Why is it Important?”

USP Guidelines for Compounding Facilities

The United States Pharmacopeia (USP) is a non-profit organization that develops standards for human and animal drugs as well as food ingredients and dietary supplements.

For pharmaceutical compounding facilities, USP has guidelines in four general chapters:

  1. USP <795> Pharmaceutical Compounding – Nonsterile Preparations
  2. USP <797> Pharmaceutical Compounding – Sterile Preparations
  3. USP <800> Hazardous Drugs – Handling in Healthcare Settings
  4. USP <825> Radiopharmaceuticals – Preparation, Compounding, Dispensing, and Repackaging

These four chapters provide guidelines for safety considerations, personnel qualification and training, facilities and engineering controls, microbiology and surface monitoring, cleaning and disinfection, and much more. Continue reading “USP Guidelines for Compounding Facilities”