USP Guidelines for Compounding Facilities

The United States Pharmacopeia (USP) is a non-profit organization that develops standards for human and animal drugs as well as food ingredients and dietary supplements.

For pharmaceutical compounding facilities, USP has guidelines in four general chapters:

  1. USP <795> Pharmaceutical Compounding – Nonsterile Preparations
  2. USP <797> Pharmaceutical Compounding – Sterile Preparations
  3. USP <800> Hazardous Drugs – Handling in Healthcare Settings
  4. USP <825> Radiopharmaceuticals – Preparation, Compounding, Dispensing, and Repackaging

These four chapters provide guidelines for safety considerations, personnel qualification and training, facilities and engineering controls, microbiology and surface monitoring, cleaning and disinfection, and much more. Continue reading “USP Guidelines for Compounding Facilities”

Proving Flow Through Chillers

Water chillers are nothing new, with nearly an estimated 100,000 units operating in North America alone. Chillers are the cooling machines of choice to condition industrial, commercial, and institutional facilities. They are used to lower the temperatures of all kinds of equipment and processes such as: robotic machinery; semiconductors; injection and blow molding machines; welding equipment; die-casting and machine tooling; paper and cement processing; power supplies; power generation stations; compressed air and gas cooling systems; medical imaging machines; chemical, drug, food and beverage production; even simply to cool potable water to desirable levels. Whether for office comfort, keeping data server centers from overheating, or specialized industrial processes, water temperature control plays a vital role in many of the behind-the-scenes activities that affect our everyday lives. Continue reading “Proving Flow Through Chillers”

How to Program a Switch for Manual Reset

Compact Low Differential Pressure Switch with Manual Reset, Series 1900MR

Several applications require manual reset switches, which are switches that need to be physically reset by an individual for a process to continue or restart. A manual reset is often needed when an area has to be inspected prior to equipment restart. This can help to ensure the safety/inspection of both equipment and other individuals in the area.

Some switches have a mechanical manual reset (such as the Dwyer Series 1900, 1831, and 1800). However, there may be a need to have a manual reset for applications beyond what these switches are designed for. If a pump is allowed to run with a clogged filter, for example, this may severely damage the pump. Continue reading “How to Program a Switch for Manual Reset”

Certificates of Calibration Explained

Dwyer Instruments, Inc. offers a variety of calibration services for new or previously purchased products. In 2019, the Dwyer Instruments, Inc. – Engineering Laboratory, located in Michigan City, IN, gained accreditation to ISO/IEC 17025:2017 through the ANSI National Accreditation Board. The Dwyer lab now offers two different types of calibration certificates for our products: a certificate of NIST calibration and an ISO/IEC 17025:2017 accredited certificate of calibration. Now that accredited calibration services are available for select Dwyer products, it is important to know the differences between these two different calibration certificates. Knowing these differences will allow you to understand which calibration certificate will best suit your needs. Continue reading “Certificates of Calibration Explained”